The Zero-Dose Learning Hub (ZDLH) established by Gavi, the Vaccine Alliance (Gavi), is focused on the outcome of timely, increased, and sustainable use of evidence to improve regional, country, and global immunization programs and policies in alignment with the Gavi 5.0 Strategy and Identify, Reach, Monitor and Measure, and Advocate (IRMMA) Framework. The semiannual update for the Gavi Board and other stakeholders highlights the ZDLH consortium’s efforts to generate and share evidence for a deeper understanding of the factors that affect the implementation and performance of strategies to identify and reach zero-dose (ZD) and under-immunized (UI) children and missed communities. It synthesizes findings, challenges, and recommendations across the IRMMA Framework emerging from the Learning Hubs.
Explore the data dashboards below and visit Related Resources to download each country's semiannual update report.
Country Learning Hubs
The ZDLH helps generate, synthesize, and share ZD data and evidence at both the global and country levels. The structure is a hub-and-spoke model: JSI, the global learning partner manages learning and evidence at the global level, and four country learning hubs (CLHs) in Bangladesh, Mali, Nigeria, and Uganda, comprised of local partners/consortiums, capture and use country-level programmatic data and evidence to provide insights on how the ZD strategy is being translated at the subnational level through improved monitoring and evidence generation.
The four Learning Hubs include:
- Bangladesh: Led by the International Center for Diarrhoeal Disease Research, Bangladesh (icddr,b) with partners Jhpiego and RedOrange Communications.
- Mali: Led by GaneshAID with the Center for Vaccine Development-Mali (CDV-Mali) and the University of Bamako.
- Nigeria: Led by the African Field Epidemiology Network (AFENET) with the African Health Budget Network (AHBN).
- Uganda: Led by Infectious Diseases Research Collaboration (IDRC) with partners PATH and Makerere University School of Public Health (MakSPH).
The Learning Hub countries were selected to ensure variation by region and context, including rural, urban, conflict, or refugee, and based on a relatively high number and proportion of ZD children. Other considerations included feasibility and risk mitigation.
ZDLH Global Consortium
In addition to the four Learning Hubs, the ZDLH mechanism includes a global consortium led by JSI Research & Training Institute, Inc. (JSI), in partnership with the International Institute of Health Management Research, New Delhi (IIHMR) and The Geneva Learning Foundation (TGLF). The global consortium provides technical and operational support to the Learning Hubs and disseminates learnings at the community, regional, national, and global levels.
Technical Assistance
As the global learning partner, ZDLH supports country learning hubs in executing their IRMMA-aligned learning agendas by offering demand-driven and collaborative capacity strengthening, technical assistance, and mentorship. During this reporting period:
- In Bangladesh, JSI supported the Political Economy Assessment and Forcibly Displaced Myanmar Nationals (FDMN) research by reviewing and refining draft reports, providing technical input on research tools and methodologies, and collaborating with icddr,b, IIHMR, and Gavi to ensure ethical and strategic alignment.
- In Mali, JSI supported the Learning Hub by co-developing the implementation research protocol, providing technical leadership on Lot Quality Assurance Sampling (LQAS) survey design and training, and ensuring high-quality data collection, strengthening the Learning Hub’s capacity to generate rigorous evidence for immunization equity.
- In Nigeria, JSI supported the Learning Hub by reviewing and advising on Decentralized Immunization Monitoring (DIM) and LQAS findings, guiding data analysis methods, and facilitating technical discussions to strengthen the interpretation and presentation of vaccine coverage and behavioral and social drivers (BeSD) of vaccination indicators by age cohort.
- In Uganda, JSI supported the Learning Hub to strengthen its theory of change and measurement strategies, facilitating outcome mapping, reviewing research tools and costing materials, and helping pivot the implementation research to document and analyze existing immunization interventions in response to Equity Accelerator Fund (EAF) delays.
Facilitating Learning and Sharing
Knowledge Translation
During this reporting period, the ZDLH finalized and published the Knowledge Translation for Zero-Dose Immunization Research toolkit as a guide for effectively transforming research findings into practical applications, ensuring that evidence-based knowledge is communicated, adopted, and used. The toolkit provides a step-by-step process for developing knowledge translation plans. It includes guiding questions, links to resources, and strategies for engaging stakeholders, particularly in ZD immunization research. The toolkit aims to close the know-do gap, promote evidence-based practices, and drive impactful changes in policies and practices. The toolkit is also available in French.
Zero-Dose Resource Library
The ZDLH resource library features a curated repository of evidence-based measurement, monitoring, and learning resources; tools; guidance; and approaches, as well as existing evidence from each country and resources generated by the ZDLH.
During this reporting period, ZDLH uploaded 27 resources to the website. The most downloaded resources included:
- Knowledge Translation for Zero-Dose Immunization Research
- Assessment of the Political Economy Context Surrounding Evidence Use for Zero-Dose Programming and Policies in Nigeria
- Closing The Immunization Gap: Enhancing Routine Immunization in Nigeria by Reaching Zero-Dose and Under-Immunized Children in Marginalized Communities: Report of a Rapid Assessment
- Gavi’s Zero-Dose Learning Hub IRMMA Aligned Interventions: Semiannual Update—Bangladesh (October 2024)
- Nigeria Zero-Dose Landscape
The following section presents data on key immunization indicators in Bangladesh. An explanation of the data sources and interpretation of the figures is presented in the text that follows.
Please note that Wisemart/eJRF data for the period of April through September 2024 are not yet available for this semiannual update and will be incorporated in the next report (October 2025).
[Coming soon]
The following section presents data on key immunization indicators in Mali. An explanation of the data sources and interpretation of the figures is presented in the text that follows.
Please note that Wisemart/eJRF data for the period of April through September 2024 are not yet available for this semiannual update and will be incorporated in the next report (October 2025).
[Coming soon]
The following section presents data on key immunization indicators in Nigeria. An explanation of the data sources and interpretation of the figures is presented in the text that follows.
Please note that Wisemart/eJRF data for the period of April through September 2024 are not yet available for this semiannual update and will be incorporated in the next report (October 2025).
[Coming soon]
The following section presents data on key immunization indicators in Uganda. An explanation of the data sources and interpretation of the figures is presented in the text that follows.
Please note that Wisemart/eJRF data for the period of April through September 2024 are not yet available for this semiannual update and will be incorporated in the next report (October 2025).
[Coming soon]