During the period July–December 2024, JSI, as the Zero-Dose Learning Hub global learning partner, continued to provide technical assistance and collaborate and co-create with the Uganda Learning Hub. This semiannual update for the Gavi, the Vaccine Alliance Board and other stakeholders highlights the Learning Hub’s efforts to leverage evidence for a deeper understanding of the factors that affect the implementation and performance of strategies to identify and reach zero-dose and under-immunized children and missed communities in Uganda. Key efforts included evaluations of the Big Catch-Up campaign and UNICEF-supported house-to-house registration as well as documentation of emerging lessons from the roll-out of Equity Accelerator Fund-supported activities. This report synthesizes findings, challenges, and recommendations emerging across the IRMMA framework.